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Anti -Apolipoprotein A I Rabbit Polyclonal Antibody
Description | Apolipoprotein A I rabbit polyclonal |
Protein full name | Apolipoprotein A-I |
Synonyms | Apo-AI, ApoA-I, Apolipoprotein A 1, Apoa1, Truncated apolipoprotein A-I, AIBP, Proapolipoprotein A-I, Apolipoprotein A I binding protein |
Immunogen | Recombinant protein corresponding to Mouse Apolipoprotein A I |
Isotype | IgG |
Purity | Affinity purification |
Subcellular location | |
Uniprot ID |
Applications
Applications | Species | Dilution | Positive Tissue |
IHC | Mouse, Rat | 1: 1900-1: 3800 | small intestine |
Background
ApoA1 is a major protein component of high density lipoproteins (HDL) which is associated with reversed cholesterol transport, lipid/cholesterol binding, lecithin/cholesterol acyltransferase (LCAT) activation and specific receptors binding. ApoA1 promotes cholesterol efflux from tissues to the liver for excretion, and it’s a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. Defects of ApoA1 cause low HDL level and systemic non-neuropathic amyloidosis. Serum concentration of ApoA1 is inversely related to the risk of developing atherosclerosis.
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).
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