Graviola is a substance that comes from a tree in the rain forests of Africa, South America, and Southeast Asia. Its scientific name is Annona muricata. It is also known as custard apple, cherimoya, guanabana, soursop and brazilian paw paw. In many countries, people use the bark, leaves, root, and fruits of this tree for traditional remedies. The active ingredient is The graviola tree, or Annona muricata, produces the sweet soursop fruit, also called custard apple, paw paw or, in many Spanish-speaking countries, guanabana. The tree reaches a height of 25 or 30 feet and produces large fruit that may reach a length of 12 inches. Although its rind is quite bitter, the fruit's flesh is soft, smooth and sweet, and provides carbohydrate as its major nutrient. Soursop also contains abundant vitamin C and several B vitamins such as thiamin, riboflavin and niacin, along with calcium, phosphorus and a small amount of iron thought to be a type of plant Annona Squamosa is medicinal effects, including insecticide, anemia, burning sensation, antiovulatory and abortifacient, stop diarrhea, treatment of dysentery, cold remedy and to clarify urine, cooling, sedative, stimulant, expectorant, compound (phytochemical) called annonaceous acetogenin